Tetsuro Hirose 50 Years Shine-Dalgarno Symposium 2023

Tetsuro Hirose

I obtained my Ph.D. from Nagoya University in 1995 and secured a staff scientist position in the laboratory of Prof.Masahiro Sugiura to study translational control and RNA editing in plant chloroplasts. Following this, I became a HFSP postdoctoral fellow at Yale University School of Medicine in 1999, working in the laboratory of Prof. Joan A Steitz, and shifted my research focus to mammals. In 2005, I established my own laboratory at National Institute for Advanced Industrial Science and Technology (AIST) in Tokyo, which is dedicated to the study of long noncoding RNAs (lncRNAs) in mammalian cells. We identified lncRNAs that serve as structural scaffolds of specific nuclear bodies. In 2013, I was appointed as a full professor at the Institute of Genetic Medicine, Hokkaido University in Sapporo, where we explored lncRNA domains to create nuclear bodies by inducing phase separation. Recently, in 2020, I joined the Graduate School of Frontier Biosciences, Osaka University, where I hold the positions of full professor and Director of the Institute for Open and Transdisciplinary Research Initiatives (OTRI).